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Pregnancy & Ovulation
Pregnancy hCG Strips - Ultra Sensitive Early Detection
Pregnancy hCG Test Strip
The Ultra Sensitive Pregnancy Test Strip incorporates a one-step approach into a total system for on-site urine pregnancy testing.
These FDA cleared pregnancy tests are 99.9% accurate and detect human chorionic gonadotropic (hCG), a hormone secreted by the developing placenta shortly after fertilization, at levels of just 10 miu/ml hCG. You may begin testing just 8 to 9 days after your ovulation date.
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HCG is a hormone produced by trophoblastic tissue and it appear s around the 8-9th day after ovulation, or around the 4th day after conception. In a 28 day cycle with ovulation occurring at day 14, HCG can be detected in urine or serum in minute quantities around day 23, or 5 days before the expected menstruation. The hormone concentration doubles approximately every 2 days and peaks between 7-12 weeks after the first day of the last menstrual period. In normal subjects, HCG in urine provides an early indication of pregnancy.
The elevated HCG levels are also associated with trophoblastic diseases and certain nontrophoblastic neoplasms. Thus, the possibility of other diseases must be eliminated before the diagnosis of pregnancy can be made. HCG consists of two subunits, alpha and beta. Alpha subunits of these various glycoprotein hormones are structurally very similar, but beta subunits differ in amino acid sequences. These differences are responsible for their biological and immunological specificity.
The Ultra Sensitive HCG Test Kit is based on the principle of immunochromatography. Each test device contains monoclonal anti-beta-HCG antibody/colloidal gold conjugate pre-dried on a pad. Monoclonal anti-alpha-HCG antibody (at the test region) and goat anti mouse IgG (at the control region) are coated on the membrane. When the absorbent pad is soaked with urine, the urine will migrate via capillary action toward the result window. If HCG is present in the urine, it reacts with anti-beta-HCG antibody/colloidal gold conjugate to form a complex which will move and be captured by anti-alpha-HCG antibodies to form a colored line in the test region. The control line is not influenced by the presence or absence of HCG in sample, and it should be present in all reactions. Absence of a colored control line in the control region is an indication of an invalid result. The detection limit for the HCG Test Kit is 10 mIU/ml HCG. Urine samples equal to or greater than 10 mIU/ml will be tested positive. Samples containing less than 10 mIU/ml HCG may also produce a very faint positive line.
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